IES Ltd.

 

 IES  

 

 IES Ltd. (Innovative Environmental Services Ltd. 以下、IES)は、2008年に設立され、主として環境科学に特化したGLP試験施設です。生態毒性試験、環境運命試験、作物代謝、各種分析試験に対応しています。施設は、スイス連邦バーゼル(Basel)市近郊にあり、近代的な建物と最先端の技術と設備でお客様にサービスを提供しています。ヨーロッパを始め、日本も含めたGlobalに農薬、化学、バイオサイドから医薬品企業まで、幅広くお客様にご愛顧頂いています。

スリーエス・ジャパンは、IESの日本総代理店となり、今後、IESとの協力体制により、日本のお客様へさらなるサービスを提供させて頂きます。

 

 SERVICES

■生態毒性試験(Aquatic and Terrestrial Ecotoxicology)

  • ・Acute and chronic studies with daphnia, algae, lemna, fish, fish eggs
  • ・Bacterial toxicity tests and biodegradation studies
  • ・Higher tier testing (e.g. pulse dose tests, tests on sediment)
  • ・Endocrine disruptor studies
  • ・Analytical support, including development and validation of methods
  • ・Honey bee laboratory studies: acute and chronic adult bee toxicity studies
  •  as well as larvae studies
  • ・Honey bee semi-field tunnel and field studies including brood development
  • ・Bumble bee laboratory, semi-field and field studies
  • ・Solitary bee laboratory, semi-field and field studies
  • ・Residue studies (honey, pollen and other matrices)
  • ・Non-Target Arthropods laboratory, extended laboratory, aged residue,
  •  semi-field and field studies
  • ・Non-Target Plants vegetative vigour and seedling emergence studies
  •  under greenhouse conditions
  • ・Soil organism (Earthworm, Collembola, Hypoaspis) and microbial activity
  •  (OECD 216 and 217) studies

■環境運命試験(Environmental Fate)

  • ・Transformation in soil (laboratory and outdoor studies) including
  •  analytical method development
  • ・Soil adsorption/desorption and time-dependent sorption studies
  • ・Transformation in aquatic systems (with or without artificial sunlight)
  • ・Aerobic mineralisation in surface water (with or without sediment)
  • ・Hydrolysis and photolysis in soil and water (direct and indirect)
  • ・Transformation in manure

■作物代謝(Crop Metabolism)

  • ・including pre-emergence, post-emergence or post-harvest applications)
  • ・Confined rotational crop studies 
  •  (greenhouse or outdoor facility with 14C-labelled compounds)
  • ・Investigations into stability during crop storage and processing.
  • ・In vitro comparative metabolism studies
  • ・In vitro skin penetration studies
  • ・Analytical support: In metabolism studies with 14C-labelled compounds,
  •  quantitative and qualitative analysis
  •  of test items and metabolites are routinely conducted using HPLC
  •  with online radiodetection
  •  (with the option of stopped flow radiodetection for low level counting). 
  •  In addition, a second contrasting system used for confirmatory
  •  analysis is customarily undertaken. LC-MS/MS with high-resolution,
  •  accurate-mass (HRAM) Orbitrap detection is used, together with on line
  •  radiodetection, for the identification of unknown components.

■各種分析試験

  • ・Method development and validation
  • ・Dose verification for all types of studies, including toxicology studies
  • ・Quantitative analysis of parent and metabolites
  • ・Identification of unknown metabolites
  • ・Residue analysis
  • ・5-batch analysis
  • ・Physicochemical studies involving analytical chemistry (e.g. water solubility, Log Pow)
  • ・Field dissipation and residue studies

 

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